BoneScience Blog — healthy aging

Most of what you read about fisetin comes from mice. In people we found four small studies, a poor-absorption problem for plain fisetin, and 34 registered trials with few results. Here is each study, the doses used, and how to read a label.

Black ginger has about ten human trials. Three 12-week trials measured less body fat than placebo, two measured a stronger grip, a single dose did nothing, and no trial ran longer than 12 weeks. Here is each one, plus the doses and what is still unknown.

NMN raised blood NAD+ in every human trial and was well tolerated in short studies. Bigger reviews found no clear benefit for blood sugar or muscle. Here is each study, plus 4 checks before you buy.

Three randomized trials asked whether taking NMN raises NAD+ in people. Here is what they found, what they did not, and three things to check before you buy an NMN.