Explore our effective micro-nutrients and premium ingredients

What is Pantothenic acid and what does it do?

Pantothenic acid (also called vitamin B5) helps turn the food you eat into the energy you need. It’s important for many functions in the body, especially making and breaking down fats.

Pantothenic acid (also known as vitamin B5) is an essential nutrient that is naturally present in some foods, added to others, and available as a dietary supplement. The main function of this water-soluble B vitamin is in the synthesis of coenzyme A (CoA) and acyl carrier protein [1,2]. CoA is essential for fatty acid synthesis and degradation, transfer of acetyl and acyl groups, and a multitude of other anabolic and catabolic processes [3,4]. Acyl carrier protein’s main role is in fatty acid synthesis [2].

A wide variety of plant and animal foods contain pantothenic acid [1]. About 85% of dietary pantothenic acid is in the form of CoA or phosphopantetheine [2,4]. These forms are converted to pantothenic acid by digestive enzymes (nucleosidases, peptidases, and phosphorylases) in the intestinal lumen and intestinal cells. Pantothenic acid is absorbed in the intestine and delivered directly into the bloodstream by active transport (and possibly simple diffusion at higher doses) [1,2,4]. Pantetheine, the dephosphorylated form of phosphopantetheine, however, is first taken up by intestinal cells and converted to pantothenic acid before being delivered into the bloodstream [2]. The intestinal flora also produces pantothenic acid, but its contribution to the total amount of pantothenic acid that the body absorbs is not known [4]. Red blood cells carry pantothenic acid throughout the body [4]. Most pantothenic acid in tissues is in the form of CoA, but smaller amounts are present as acyl carrier protein or free pantothenic acid [1,4].

How much Pantothenic acid do I need?

The amount of pantothenic acid you need depends on your age and sex. Average daily recommended amounts are listed below in milligrams (mg):



  Birth to 6 months

1.7 mg  

  Infants 7–12 months

1.8 mg  

  Children 1–3 years

2 mg  

  Children 4–8 years

3 mg  

  Children 9–13 years

4 mg  

  Teens 14–18 years

5 mg  

  Adults 19 years and older

5 mg  

  Pregnant teens and women

6 mg  

  Breastfeeding teens and women

7 mg  

What happens if I don’t get enough Pantothenic acid?

Pantothenic acid deficiency is very rare in the United States. Severe deficiency can cause numbness and burning of the hands and feet, headache, extreme tiredness, irritability, restlessness, sleeping problems, stomach pain, heartburn, diarrhea, nausea, vomiting, and loss of appetite.

What are some effects of Pantothenic acid on health?

Scientists are studying pantothenic acid to understand how it affects health. Here’s one example of what this research has shown.

High cholesterol and triglyceride levels

The form of pantothenic acid called pantethine is being studied to see if it helps lower total cholesterol, low-density lipoprotein (LDL or “bad”) cholesterol, and triglyceride levels. It’s also being studied to see if it raises levels of high-density lipoprotein (HDL or “good”) cholesterol. The results of these studies so far are promising, but more research is needed to understand the effects of pantethine dietary supplements taken alone or combined with a heart-healthy diet.

Can Pantothenic acid be harmful?

Pantothenic acid is safe, even at high doses. However, taking very high doses of pantothenic acid supplements (such as 10,000 mg per day) can cause an upset stomach and diarrhea.

Where can I find out more about Pantothenic acid?

For general information about pantothenic acid:
For more information on food sources of pantothenic acid:
o U.S. Department of Agriculture’s (USDA) FoodData Central
o Nutrient List for pantothenic acid (listed by food or by pantothenic acid content), USDA
For more advice on choosing dietary supplements:
• For information about building a healthy dietary pattern:


1. Miller JW, Rucker RB. Pantothenic acid. In: Erdman JW, Macdonald IA, Zeisel SH, eds. Present Knowledge in Nutrition. 10th ed. Washington, DC: Wiley-Blackwell; 2012:375-90.

2. Sweetman L. Pantothenic acid. In: Coates PM, Betz JM, Blackman MR, et al., eds. Encyclopedia of Dietary Supplements. 2nd ed. London and New York: Informa Healthcare; 2010:604-11.

3. Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: National Academy Press; 1998.

4. Trumbo PR. Pantothenic acid. In: Ross AC, Caballero B, Cousins RJ, et al., eds. Modern Nutrition in Health and Disease. 11th ed. Baltimore, MD: Lippincott Williams & Wilkins; 2014:351-7.

5. Health information data from U.S. National Institutes of Health.

Better than others

Nine medical doctors used their research findings to develop Dr’s Grow UP in the biotech lab. The result is a product containing 22 ingredients mixed in the perfect proportions to maximize bone health and height development. 

Why Bone Science?

Science-Backed Formulations

Carrying out extensive research and keeping up-to-date with the latest scientific findings is our key to develop superior formulations. 

Best Growth Support for Kids & Teenagers

Our products contain essential ingredients for a healthy bone and height development of kids from 10 years and teenagers. 

Fighting Aging Effects

We are dedicated to create formulations that delay and restrict the extent of adult’s bone density decrease.

Unmatched Product Quality

Only 100% natural ingredients that contain no soy, no gluten, no GMOs, no maltodextrin, and no artificial flavors, colors, or preservatives. 

Product Safety 

All of our products are manufactured in the US in an FDA and NSF cGMP registered facility.