PRIME BERBERINE

Supports healthy blood sugar levels*

Promotes healthy cholesterol balance*

Enhances cell health for youthful energy*

Berberine: Naturally Ignites Your Metabolism

and Boosts Energy from Within

Sourced from the roots and bark of ancient barberry plants, Berberine is a time-honored botanical that’s been used for centuries

—tracing back to 650 BC. But modern science now confirms what traditional wisdom knew all along.

Berberine activates AMPK, a key cellular enzyme often referred to as the body’s “metabolic master switch.”

The result? Better energy balance, enhanced fat metabolism, and support for overall metabolic health.

While most supplements offer basic berberine, Prime Berberine stands out with a powerful

7X complex formula combining patented Berbevis® phytosome, Ceylon cinnamon, banaba, and BioPerine®.

This advanced blend delivers up to 9.6x higher absorption than standard berberine — for results you can truly feel.

How Prime Berberine

works for you

Healthy Metabolism & Blood Sugar Balance

  • Promotes balanced glucose metabolism and supports insulin sensitivity
  • Helps maintain healthy levels of LDL, HDL, and triglycerides
  • Includes time-tested botanicals traditionally used to support metabolic health


Clinically Proven Absorption System

  • Features Berbevis®—a next-gen berberine phytosome for optimal delivery
  • BioPerine® enhances the uptake of every key nutrient
  • Includes cellular transport-supporting phospholipids and natural polyphenols

Heart & Cellular Wellness

  • Zinc and quercetin offer antioxidant defense and immune support
  • Promotes healthy blood vessel function and fights oxidative stress
  • Promotes daily cellular energy, clarity, and metabolic vitality


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


ABOUT

PRIME BERBERINE

Prime Berberine – Key Benefits at a Glance

  • Supports healthy blood sugar metabolism and insulin sensitivity*
  • Promotes balanced cholesterol and lipid profiles*
  • Enhances mitochondrial energy for sustained vitality*
  • Encourages youthful cellular function and resilience*
  • Helps maintain metabolic balance and cardiovascular wellness*

Is Prime Berberine Right for You?

  • You’re focused on maintaining balanced blood sugar and metabolic health*
  • You want nutritional support for healthy cholesterol levels*
  • You’re navigating PCOS and seeking plant-based, metabolic support*
  • You’re addressing metabolic syndrome and want targeted nutrient support*
  • You’re aiming to support a healthy gut microbiome for full-body wellness*
  • You care about long-term cardiovascular and cellular function*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Why Choose Prime Berberine?

Not all berberine is created equal.


Most formulas use outdated delivery methods with poor absorption.

Prime Berberine features Berbevis® Phytosome, clinically shown to boost bioavailability by 9.6x.

Enhanced with BioPerine® for maximum uptake and real impact. And we didn’t stop at berberine.

Each capsule includes a clinically designed blend of 7 synergistic ingredients

targeting blood sugar, cholesterol, and cellular vitality in one smart dose.


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


How Prime Berberine Compares

Supplement Facts

 

Amount Per Serving

%DV

Zinc (as Zinc Gluconate)

9 mg

82%

Berbevis® Berberine Phospholipids

500 mg

†

Ceylon cinnamon

(Cinnamomum verum) 

100 mg

†

Banaba

(Lagerstoemia speciosa) Leaf Extract 

30 mg

†

Bitter Melon

(Momordica charantia) Fruit Extract 

30 mg

†

Quercetin (as Quercetin dihydrate) 

30 mg

†

Bioperine® Black Pepper Extract

5 mg

†


† Daily Value (DV) not established.

Hypromellose, MCT Oil, Magnesium Stearate, Stearic Acid, Silicon Dioxide, Microcrystalline Cellulose


Contains: NO Allergens


Berbevis® is a registered trademark of Indena SpA, Italy


BioPerine® is a registered trademark of Sabinsa Corporation. 

What Makes Berbevis® Different?

Developed by Indena®, a global leader in botanical innovation for over a century, Berbevis® uses cutting-edge Phytosome® delivery technology to unlock berberine’s full potential. Clinically validated for dramatically better absorption and bioavailability, allowing your body to benefit from berberine’s effects more quickly and reliably.

Unlike standard forms that require high doses to be effective, Berbevis® delivers targeted metabolic support with lower amounts—reducing the burden on your system while still promoting healthy blood sugar levels, cholesterol balance, and energy metabolism. It’s berberine reimagined for modern wellness.

Our unique formulation

Clinically Enhanced Absorption

At the core of Prime Berberine is Berbevis®, a clinically tested, patented Phytosome® ingredient by Indena® of Italy. It delivers up to 9.6x greater absorption than standard berberine, without the digestive discomfort.


The Power of the 7X Formula

  • More than just berberine. Each capsule blends Berbevis® 500mg with:
  • Ceylon Cinnamon for balanced blood sugar
  • Banaba Leaf & Bitter Melon for comprehensive metabolic support
  • BioPerine® to enhance nutrient absorption
  • Zinc & Quercetin to support immunity and cellular protection


Made in the USA with Integrity

Produced in a GMP-certified facility in the United States, every batch meets rigorous standards for purity, safety, and label accuracy.


No allergens. No GMOs. No artificial additives.

Just clean, science-backed ingredients.


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


PRIME

BERBERINE


More than just berberine, a holistic approach to metabolic health that supports blood sugar balance, sustained energy, and long-term vitality.


Metabolic Balance Starts Here


Whether you're managing blood sugar levels, improving cholesterol profiles, or simply supporting your heart and metabolic health, Prime Berberine is tailored for individuals who want lasting, proactive support. Ideal for those with fluctuating blood sugar, early signs of metabolic imbalance, or those pairing supplements with dietary changes.


Support that goes deep – Right to your cells

Formulated with BioPerine® for superior absorption, Prime Berberine also supports cellular resilience, antioxidant defense, and mitochondrial energy.

Perfect for anyone dealing with low energy, seeking youthful vitality, or interested in anti-aging wellness from the inside out.


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


Ahead of Our Competition


Our research team is committed to gaining new insights into osteology (the study of bones) to promote your bone health and wellbeing. 


We use our knowledge to develop scientifically sound products that our customers can trust. 

Why BoneScience?


Turn Possibility to reality.

Science-Backed Formulations

Carrying out extensive research and keeping up-to-date with the latest scientific findings is our key to develop superior formulations. 


Best Growth Support for Kids & Teenagers*

Our products contain essential ingredients for a healthy bone and height development of kids from 10 years and teenagers.* 


Fighting Aging Effects

We are dedicated to create formulations that delay and restrict the extent of adult’s bone density decrease.*


Unmatched Product Quality

Only 100% natural ingredients that contain no soy, no gluten, no GMOs, no maltodextrin, and no artificial flavors, colors, or preservatives. 


Product Safety 

All of our products are manufactured in the US in an FDA and NSF cGMP registered facility.